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Long-term hypercalcaemia ordinarily causes calcification of sentimental tissue and its major outcomes: for example, calcification can cause lack of elasticity of vascular walls and disruption of laminar blood flow—and thence to plaque rupture and thrombosis.
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Parathyroid hormone and vitamin D endorse the development of bone by making it possible for and enhancing the deposition of calcium ions there, allowing for immediate bone turnover with out influencing bone mass or mineral information.[8] When plasma calcium degrees drop, mobile surface receptors are activated plus the secretion of parathyroid hormone occurs; it then proceeds to promote the entry of calcium into your plasma pool by taking it from specific kidney, intestine, and bone cells, Together with the bone-forming motion of parathyroid hormone becoming antagonised by calcitonin, whose secretion boosts with expanding plasma calcium ranges.[59] Irregular serum concentrations
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Calcium, strontium, barium, and radium are constantly regarded as being alkaline earth metals; the lighter beryllium and magnesium, also in team 2 from the periodic table, in many cases are bundled as well. Nevertheless, beryllium and magnesium differ considerably from the other members of the group of their Actual physical and chemical actions: they behave extra like aluminium and zinc respectively and possess many of the weaker metallic character with the article-changeover metals, And that's why the standard definition from the term "alkaline earth metallic" excludes them.[eleven] Physical properties
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